50th MilliporeSigma Lectureship | Structural Insights into TRP Channel Gating: Visualizing a Polymodal Signal Integrator

Thursday, November 2, 7:00pm - 8:00pm (EDT)

Time shown in-05:00 America, New York

Structural Insights into TRP Channel Gating: Visualizing a Polymodal Signal Integrator
The capsaicin receptor, TRPV1, is a heat-activated ion channel that is modulated by numerous inflammatory and pro-algesic agents. This ability to serve as a complex polymodal signal integrator underlies the channel's contribution to both acute and persistent pain. Elucidating structural and allosteric mechanisms underlying such polymodality is key to understanding the function and therapeutic potential of TRPV1 and other members of this diverse ion channel superfamily.

Dr. David Julius
Professor and Chair of the Department of Physiology at the University of California San Francisco
2021 Nobel Laureate in Physiology or Medicine

Refreshments at 3:30pm.
No RSVP necessary.
Host: Edward A. Dennis, Ph.D.

Add to Calendar 2023/11/02 16:00:00 2023/11/02 17:00:00 America/Los_Angeles 50th MilliporeSigma Lectureship | Structural Insights into TRP Channel Gating: Visualizing a Polymodal Signal Integrator Structural Insights into TRP Channel Gating: Visualizing a Polymodal Signal Integrator
The capsaicin receptor, TRPV1, is a heat-activated ion channel that is modulated by numerous inflammatory and pro-algesic agents. This ability to serve as a complex polymodal signal integrator underlies the channel's contribution to both acute and persistent pain. Elucidating structural and allosteric mechanisms underlying such polymodality is key to understanding the function and therapeutic potential of TRPV1 and other members of this diverse ion channel superfamily.

Dr. David Julius
Professor and Chair of the Department of Physiology at the University of California San Francisco
2021 Nobel Laureate in Physiology or Medicine

Refreshments at 3:30pm.
No RSVP necessary.
Host: Edward A. Dennis, Ph.D. Health Sciences Education Center Auditorium, Lower Level, Skaggs School of Pharmacy & Pharmaceutical Sciences Building false MM/DD/YYYY 60 OPAQUE aRHTJAtebzuytgVCsmlE218689

Health Sciences Education Center Auditorium, Lower Level, Skaggs School of Pharmacy & Pharmaceutical Sciences Building

Milda Simonaitis, msimonaitis@health.ucsd.edu

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